The increasing emergence of Mycobacterium tuberculosis (Mtb) strains resistant to traditional anti-tuberculosis drugs has alarmed health services worldwide.The search for new therapeutic targets and effective drugs that counteract the virulence and multiplication of Mtb represents a challenge for the scientific community.Several studies have consid

Pipe routing and clamp layout for aeroengine are NP-hard computational problems and complex engineering design processes.Besides space constraints and engineering rules, there are assembly constraints between pipes and clamps, which usually lead to repeatedly modifications between pipe routing and clamp layout designs.In order to solve the problems

Three stories narrate professional and design practices that expand the Galaxy of Design, testifying to comprehensive experimental approaches, acqua micellare from the products produced, to the languages and techniques employed, to the themes and meanings.A studio, a scholarly research agency and a professional, who further shift and shred the boun

Thelephora ganbajun Zang, a rare wild macrofungus, has significant culinary and medicinal value.However, it also has a high cost attributed to its inability to achieve artificial cultivation and its strict environmental requirements.To reveal the intricacies of its development, we conducted a comprehensive analysis of the proteome and metabolome in

In the brain, the heme oxygenase (HO) system has been reported to be very active and its modulation seems to play a crucial role in the MBFU Ballast pathophysiology of neurodegenerative disorders.Hemin as HO-1 inducer has been shown to attenuate neuronal injury so the goal of this study was to assess the effect of hemin therapy on the acute stress